Strategy for Cross-Protection among Shigella flexneri Serotypes

Strategy for cross-protection among Shigella flexneri serotypes.

Based upon the lipopolysaccharide (LPS) structure and antigenicity of Shigella group B, a strategy for broad cross-protection against 14 Shigella flexneri serotypes was designed. This strategy involves the use of two S. flexneri serotypes (2a and 3a), which together bear the all of the major antigenic group factors of this group. The novel attenuated strains used in these studies were S. flexne...

Serotypes of Shigella flexneri found in children in Mexico City.

Previous studies (1) have shown that organisms belonging to the genus Shigella are the most common bacteria1 pathogens found in children over six months old with gastroenteritis, in Mexico City. Shigella Jlexneri has been the most prevalent species isolated in this city (l-3). The purpose of this paper is to report the incidence of the various serotypes of Sh. Jllezneri isolated from children i...

Keratitis due to Shigella flexneri.

Multiresistant Shigella flexneri isolates were cultured from the cornea and stool of a girl. Genetic analysis showed the isolates were identical. Shigella spp. are rare causes of ulcerative keratitis; there have only been 14 published cases since 1943. Although prognosis after local treatment is good, shigellosis is a systemic infection, possibly leading to dehydration.

Shigella boydii serotypes in Egypt.

While Shigella boydii serotypes have been reported on numerous occasions from many parts of the world (Weil and Saphra, 1953), they rarely have comprised more than a small proportion of the total number of Shigella found, and knowledge of their distribution, cultural characteristics, immunological relationships and pathogenicity is incomplete in some respects. This is particularly true of the m...

Fulminating encephalopathy and Shigella flexneri infection.